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Below are some selective articles, books, patent, and chapters that are developed at or associated with CAMIS:


Selected articles from 2000 -2008

  1. Kingsbury JS, Laue TM, Klimtchuk ES, Theberge R, Costello CE, Connors LH. The modulation of transthyretin tetramer stability by cysteine-10 adducts and the drug diflunisal: Direct analysis by fluorescence-detected analytical ultracentrifugation. J Biol Chem 2008;238:11887-11896
  2. Laue TM, Austin JB, Rau DA. A light intensity measurement system for the analytical ultracentrifuge. Progress in Colloid and Polymer Science 2006;131:1-8
  3. Moody TP, Kingsbury JS, Durant JA, Wilson TJ, Chase SF, Laue TM. Valence and anion binding of bovine ribonuclease A between pH 6 and 8. Anal Biochem 2005;336:243-252
  4. Bou-Abdallah F, Adinolfi S, Pastore A, Laue TM, Chasteen ND. Iron binding and oxidation kinetics in frataxin CyaY of Escherichia coli. J Mol Biol 2004;341:605-615
  5. Correia JJ, Laue T, Stafford WF. Preface to festschrift for Dave Yphantis. Biophys Chem 2004;108:1-4
  6. Correia JJ, Johnson ML, Laue T, Stafford WF, Williams RC. Spinning with Dave: David Yphantis's contributions to ultracentrifugation. Biophys Chem 2004;108:23-42
  7. Jacobs A, Hartman K, Laue T, Caffrey M. Sedimentation velocity studies of the high-molecular weight aggregates of the HIV gp41 ectodomain. Protein Sci 2004;13:2811-2813
  8. Jiang S, Jacobs A, Laue TM, Caffrey M. Solution structure of the coxsackievirus and adenovirus receptor domain 1. Biochemistry 2004;43:1847-1853
  9. Laue T. Analytical ultracentrifugation: a powerful 'new' technology in drug discovery. Drug Discovery Today: Technologies 2004;1:309-315
  10. MacGregor IK, Anderson AL, Laue TM. Fluorescence detection for the XLI analytical ultracentrifuge. Biophys Chem 2004;108:165-185
  11. Moody TP, Shepard HK. Nonequilibrium thermodynamics of membrane-confined electrophoresis. Biophys Chem 2004;108:51-76
  12. Arcidiacono S, Mello CM, Butler M, et al. Aqueous Processing and Fiber Spinning of Recombinant Spider Silks. Macromol 2002;35:1262-1266
  13. Durant J, Chen C, Laue TM, Moody TP, Allison SA. Use of T4 lysozyme charge mutants to examine electrophoretic models. Biophys Chem 2002;101-102:593-609
  14. Grady JK, Zang J, Laue TM, Arosio P, Chasteen ND. Characterization of the H- and L-subunit ratios of ferritins by sodium dodecyl sulfate-capillary gel electrophoresis. Anal Biochem 2002;302:263-268
  15. Hattan SJ, Laue TM, Chasteen ND. Purification and characterization of a novel calcium binding protein from the extrapallial fluid of the mollusc, Mytilus edulis . J Biol Chem 2001;276:4461-4468
  16. Laue TM. Biophysical studies by ultracentrifugation. Curr Opin Struct Biol 2001;11:579-583
  17. Kar SR, Kingsbury JS, Lewis MS, Laue TM, Schuck P. Analysis of Transport Experiments using Pseudo-absorbance data. Anal Biochem 2000;285:135-142
  18. Laue TM. Sedimentation. Encyclopedia of Life Sciences . 2000.
  19. Tang YY, Crute BE, Kelley JJ, et al. Biophysical characterization of interactions between the core binding factor alpha and beta subunits and DNA. FEBS Lett 2000;470:167-172

Selected articles page 1984 -1999

  1. Allison SA, Wang H, Laue TM, Wilson TJ, Wooll JO. Visualizing Ion Relaxation in the Transport of Short DNA Fragments. Biophys J 1999;76:2488-2501
  2. Coleman J, Eaton S, Merkel G, Skalka AM, Laue TM. Characterization of the Self Association of Avian Sarcoma virus integrase by Analytical Ultracentrifugation. J Biol Chem 1999;274:32842-32846
  3. Laue TM, Stafford WF, III. Modern applications of analytical ultracentrifugation. Annu Rev Biophys Biomol Struct 1999;28:75-100
  4. Laue TM. An arrayable flow-through microcentrifuge for high-throughput instrumentation-a matter of scale. Proc Natl Acad Sci U S A 1999;96:1163
  5. Laue TM, Shepard HK, Ridgeway TM, Moody TP, Wilson TJ. Membrane-Confined Analytical Electrophoresis. Methods Enzymol 1998;295:494-518
  6. Ridgeway TM, Hayes DB, Moody TP, et al. An Apparatus for Membrane-confined Analytical Electrophoresis. Electrophoresis 1998;19:1611-1619
  7. Laue TM, Ridgeway TM, Wooll JO, et al. Insights from a New Analytical Electrophoresis Apparatus. J Pharm Sci 1997;85:1331-1335
  8. Laue TM. Advances in Sedimentation Velocity Analysis. Biophys J 1997;72:395-396
  9. Rusinova E, Ross JBA, Laue TM, Sowers LC, Senear DF. Linkage between operator binding and dimer to octamer self-assembly of bacteriophage lambda c1 repressor. Biochemistry 1997;36:12994-13003
  10. Laue TM. Solution Interaction Analysis: Choosing Which Optical System of the Optima XL-I Analytical Ultracentrifuge to Use. 1996. Fullerton, CA, Beckman Instruments.
  11. Moody TP, Donovan MA, Laue TM. Turbidimetric Studies of Limulus Coagulin Gel Formation. Biophys J 1996;71:2012-2021
  12. Laue TM. Sedimentation Equilibrium as a Thermodynamic Tool. Methods Enzymol 1995;259:427-452
  13. Laue TM, Takagi T. The Future of Analytical Ultracentrifugation. Protein, Nucleic Acid and Enzyme 1994;39:147-155
  14. Laue TM, Anderson AL, Demaine PD. An on-line interferometer for the XL-A ultracentrifuge. Prog in Coll and Polymer Sci 1994;94:74-81
  15. Liu J, Laue TM, Choi HU, Tang LH, Rosenberg LC. The Self-association of Biglycan from Bovine Articular Cartilage. J Biol Chem 1994;269:28366-28373
  16. Ridgeway TM, Hayes DB, Anderson AL, et al. Possible Clinical Applications for direct Molecular Charge Determination by Equilibrium Electrophoresis. SPIE Proceedings 1994;2136:263-274
  17. Yphantis DA, Lary JW, Stafford WF, et al. On Line Data Acqusition for the Rayleigh Interference Optical System of the Analytical Ultracentrifuge. In:Schuster TM, Laue T M, eds. Modern Analytical Ultracentrifugation: Acquisition and Interpretation of Data for Biological and Synthetic Polymer Systems. Boston, MA: Birkhauser, 1994:209-226
  18. Laue TM. Real-time interferometry in the ultracentrifuge. SPIE Proceedings 1993;1895:18-26
  19. Waxman E, Laws WR, Laue TM, Nemerson Y, Ross JBA. Human Factor VIIa and Its Complex with Soluble Tissue Factor: Evaluation of Asymmetry and Conformational Dynamics by Ultracentrifugation and Flourescence Anisotropy Decay Methods. Biochemistry 1993;32:3005-3012
  20. Laue TM. Short Column Sedimentation Equilibrium Analysis for Rapid Characterization of Macromolecules in Solution. 1-8. 1992. Palo Alto, CA, Beckman Instruments, Inc.
  21. Olsen PH, Esmon NL, Esmon CT, Laue TM. Ca2+ Depedence of the Interactions between Protein C, Thrombin, and the Elastase Fragment of Thrombomodulin. Analysis by Ultracentrifugation. Biochemistry 1992;31:746-754
  22. Waxman E, Ross JBA, Laue TM, et al. Tissue Factor and Its Extracellular Soluble Domain: The Relationship between Intermolecular Association with Factor VIIa and Enzymatic Activity of the Complex. Biochemistry 1992;31:3998-4003
  23. Donovan MA, Laue TM. A Novel Trypsin Inhibitor from the Hemolymph of the Horseshoe Crab Limulus polyphemus. J Biol Chem 1991;266:2121-2125
  24. Rosenberg LC, Choi HU, Tang LH, et al. Proteoglycans of Bovine Articular Cartilage. The effects of divalent cations on the biochemical properties of link protein. J Biol Chem 1991;266:7016-7024
  25. Laue TM, Rhodes.D.G. Determination of Size, Molecular Weight, and Presence of Subunits. Methods Enzymol 1990;182:566-587
  26. Padmanabhan S, Marqusee S, Ridgeway TM, Laue TM, Baldwin RL. Relative helix-forming tendencies of nonpolar amino acids. Nature 1990;344:268-270
  27. Rhodes DG, Laue TM. Determination of Purity. Methods Enzymol 1990;182:555-565
  28. Laue TM. Ultracentrifugation. Encycl of Polym Sci and Eng 1989;17:54-76
  29. Laue TM, Hazard AL, Ridgeway TM, Yphantis DA. Direct Determination of Macromolecular Charge by Equilibrium Electrophoresis. Anal Biochem 1989;182:377-382
  30. Luckow EA, Lyons DA, Ridgeway TM, Esmon CT, Laue TM. Interaction of Clotting Factor V Heavy Chain with Prothrombin and Prethrombin 1 and Role of Activated Protein C in Regulating This Interaction: Analysis by Analytical Ultracentrifugation. Biochemistry 1989;28:2348-2354
  31. Winnard PT, Esmon CT, Laue TM. The Molecular Weight and Oligomerization of Rabbit Thrombomodulin as Assessed by Sedimentation Equilibrium. Arch Biochem Biophys 1989;269:339-344
  32. Laue TM, Johnson AE, Esmon CT, Yphantis DA. Structure of Bovine Blood Coagulation Factor Va. Determination of the Subunit Associations, Molecular Weights, and Asymmetries by Analytical Ultracentrifugation. Biochemistry 1984;23:1339-1348
  33. Laue TM, Yphantis DA, Rhodes.D.G. Rapid Precision Interferometry for the Analytical Ultracentrifuge III. Determination of Period of Rotation, Frequency of Rotation, and Elapsed Time. Anal Biochem 1984;143:103-112
  34. Yphantis DA, Laue TM, Anderson IA. Rapid precision Interferometry for the Analytical Ultracentrifuge. II. A Laser Controller Based on a Rate-Multiplying Circuit. Anal Biochem 1984;143:95-102


  1. Schuster TM, Laue TM. Modern Analytical Ultracentrifugation: Acquisition and Interpretation of Data for Biological and Synthetic Polymer Systems. Boston: Birkhäuser, 1994:1-351
  2. Bonner, R.F., Cohn, G.E., Laue, T.M. and Priezzhev, A.V. (eds.) "Biochemical Diagnostic Instrumentation" (1994), SPIE Proceedings, Vol. 2136, 354 pp., SPIE, Bellingham, WA.


  1. 1. Laue TM, Anderson AL, Weber BJ. Prototype fluorimeter for the XLA/XLI analytical ultracentrifuge. In:Cohn EJ, soper S A, eds. Ultrasensitive Biochemical Diagnostics II. Bellingham, WA: SPIE, 1997:196-204
  2. Hayes DB, Laue TM. A Graphical Method for Determining the Ideality of a Sedimenting Boundary. In:Schuster TM, Laue T M, eds. Modern Analytical Ultracentrifugation. Boston: Birkhäuser, 1994:245-258
  3. Ross JBA, Hasselbacher CA, Kumosinski TF, et al. Testing a Model of the Extracellular Domain of Human Tissue Consistent with Fourier Transform Infrared Spectroscopy. Molecular Modeling. American Chemical Society, 1994:113-122
  4. Yphantis DA, Lary JW, Stafford WF, et al. On Line Data Acqusition for the Rayleigh Interference Optical System of the Analytical Ultracentrifuge. In:Schuster TM, Laue T M, eds. Modern Analytical Ultracentrifugation: Acquisition and Interpretation of Data for Biological and Synthetic Polymer Systems. Boston, MA: Birkhäuser, 1994:209-226
  5. Waxman E, Laws WR, Laue TM, Ross JBA. Refining Hyrdodynamic Shapes of Proteins: The Combination of Data from Analytical Ultracentrifugation and Time-Resolved Fluoresence Anisotropy Decay. In:Schuster TM, Laue T M, eds. Modern Analytical Ultracentrifugation. Boston: Birkhäuser, 1993:189-205
  6. Laue TM. On-Line Data Acquisition and Analysis from the Rayleigh Interferometer. In:Harding SE, Rowe A J, Horton J C, eds. Analytical Ultracentrifugation in Biology and Polymer Science. Cambridge: The Royal Society of Chemistry, 1992:63-89
  7. Laue TM, Shah BD, Ridgeway TM, Pelletier SL. Computer-aided Interpretation of Analytical Sedimentation Data For Proteins. In:Harding SE, Rowe A J, Horton J C, eds. Analytical Ultracentrifugation in Biochemistry and Polymer Science. Royal Society of Chemistry, 1991:90-125


  1. Laue TM, Yphantis DA, Hazard AL. Apparatus and method for macromolecular charge determination. United States Patent 305,107[4,994,161]. 1991.