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Capillary Electrophoresis

Capillary electrophoresis (CE) provides first principle insight into the solution charge of macromolecules. Electrophoretic mobility, effective charge and diffusion coefficient determinations provide novel measurements of hydrodynamic and electro-hydrodynamic properties. CE offers some advantages to MCE in valence determination:

  • Speed of data acquisition
  • Low sample volume required
  • Automated data collection
An animation of CE
An Animation of CE
With permission from the University of Warsaw Department of Chemistry: http://www.chem.uw.edu.pl/people/AMyslinski/informator_07/zdchn.html

Other Capillary electrophoresis

The primary focus of CE at CAMIS is for valence determination, (see reference at bottom); however, CE is a versatile instrument capable of many types of electrophoresis.

CE reference:

Chase SF, Laue TM. The determination of protein valence by capillary electrophoresis. P/ACE Setter 2008;12:1-12. (PDF 3.24 MB)