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Welcome to CAMIS

CAMIS - The Center to Advance Molecular Interaction Science at the University of New Hampshire develops unique instruments and first-principle methods to characterize molecular interactions in otherwise intractable chemical systems. CAMIS director Thomas M. Laue, Ph.D., is known worldwide for his expertise in analytical ultracentrifugation and his design of sophisticated data acquisition hardware and software.

CAMIS has developed:

Fluorescence detection system
  • Advanced optical detection and data acquisition systems for the analytical ultracentrifuge.
    • A fluorescence detection optical system (AU-FDS) has been licensed to Aviv Biomedical.
    • Robust operating software is currently running the AuFDS and interactive data analysis software, including a simulation version that can be used for training.
    • AUC components (sample cells, rotors), peripheral systems and high-throughput solutions have been developed and are now licensed to Spin Analytical, Inc.
  • Prototype analytical membrane-confined electrophoresis (MCE) instrument that accurately measures the valence of macromolecules, essential information in protein chemistry and small molecule research.

Future plans:

Surface plasmon coupled emission biosensor:

Advance prototype to commercial product in collaboration with the Center for Fluorescence Spectroscopy, University of North Texas. Potential applications in defense, pharmaceuticals, biomedical diagnostics, food quality.

Leading academic collaborators outside UNH:

  • Walter Stafford, Boston Biomedical Research Institute
  • Zygmunt Gryczynski, Center for Fluorescence Spectroscopy, University of North Texas
  • Ed Eisenstein, Center for Advanced Research in Biotechnology, University of Maryland
  • Borreis Demeler, University of Texas Health Science Center
  • John J. Correia, University of Mississippi Medical Center
  • David Myszka, Center for Biomolecular Interaction Analysis, University of Utah
  • Jeffrey Hansen, Colorado State University
  • Alexander Ross, Core Spectroscopy Facility for Structural Biology, University of Montana, Missoula
  • Jonathan Brad Chaires, University of Louisville
  • Qiao Lin, Columbia University
  • Richard Neubig, University of Michigan, Ann Arbor
  • Kenneth Christensen, Clemson University